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Metabolic disposition of piperine in the rat.

Ganesh Bhat, B. and Chandrasekhara, N. (1987) Metabolic disposition of piperine in the rat. Toxicology, 44 (1). 99-106, 17 ref..

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After oral administration of piperine (170 mg/kg) to rats, the metabolites in bile and urine were examined by TLC, HPLC and combined GC-MS. 4 metabolites of piperine, viz. piperonylic acid, piperonyl alcohol, piperonal and vanillic acid were identified in the free form in 0-96 h urine whereas only piperic acid was detected in 0-6 h bile. Based on these results, a pathway for the biotransformation of piperine in rats is proposed. [See also preceding abstr.]

Item Type: Article
Uncontrolled Keywords: SPICES-; piperine, decomposition metabolic of; ALKALOIDS-; DECOMPOSITION-
Subjects: 600 Technology > 08 Food technology > 30 Spices/Condiments
600 Technology > 01 Medical sciences > 12 Metabolism
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 17 Jun 2011 10:48
Last Modified: 28 Dec 2011 09:52
URI: http://ir.cftri.com/id/eprint/6307

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