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Finger millet (Eleusine coracana) – An Economically viable source for Antihypercholesterolemic Metabolites Production by Monascus purpureus

Venkateswaran, V. and Vijayalakshmi, G. (2010) Finger millet (Eleusine coracana) – An Economically viable source for Antihypercholesterolemic Metabolites Production by Monascus purpureus. Journal of Food Science and Technology, 47 (4). pp. 426-431.

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Abstract

Rice, parboiled rice, fi nger millet, germinated fi nger millet, broken wheat, njavara (medicinal rice), sorghum and maize were used as substrates for solid state fermentation of Monascus purpureus at 28°C for 7 days using 2% seed medium as inoculum for the production of its metabolites. The fungus exhibited good growth in all the substrates. The fermented substrates were dried at 45°C and analysed for antihypercholesterolemic metabolite statins by standardized HPLC method and dietary sterol contents by spectrophotometric method using reference standards of statin (pravastatin and lovastatin) and cholesterol, respectively. Germinated fi nger millet yielded higher total statin production of 5.2 g/kg dry wt with pravastatin and lovastatin content of 4.9 and 0.37 g/kg dry wt respectively than other substrates which range from 1.04–4.41 g/kg. In addition to statin, monascus fermented germinated fi nger millet yielded dietary sterol of 0.053 g/kg dry wt which is 7.6 folds higher than the control. The value addition of fi nger millet by germination and fermentation with Monascus purpureus provides scope for development of functional food.

Item Type: Article
Uncontrolled Keywords: Monascus purpureus Finger millet Eleusine coracana Antihypercholesterolemic Statin Dietary sterol
Subjects: 500 Natural Sciences and Mathematics > 07 Life Sciences > 04 Microbiology > 04 Fungi
600 Technology > 01 Medical sciences > 04 Diabetes Mellitus
600 Technology > 08 Food technology > 21 Cereals > 05 Ragi (Finger Millet)
Divisions: Food Microbiology
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 28 Sep 2010 07:12
Last Modified: 28 Dec 2011 10:19
URI: http://ir.cftri.com/id/eprint/9730

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