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Isolation of ellagic acid from the aqueous extract of the roots of Decalepis hamiltonii: antioxidant activity and cytoprotective effect.

Anup, Srivastava and Jagan Mohan Rao, L. and Shivanandappa, T (2007) Isolation of ellagic acid from the aqueous extract of the roots of Decalepis hamiltonii: antioxidant activity and cytoprotective effect. Food Chemistry, 103 (1). pp. 224-233.

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Abstract

Roots of Decalepis hamiltonii are consumed as pickles and as a beverage and are believed to possess health-promoting properties. Roots of D. hamiltonii exhibit antioxidant properties. We have isolated an antioxidant compound from the aqueous extract of the roots of D. hamiltonii and identified it as ellagic acid (EA), based on NMR and MS. EA exhibited free radical-scavenging activity, inhibited LDL oxidation and showed cytoprotective effect against xenobiotic-induced oxidative stress in Ehrlich Ascites tumour cells. EA is a new addition to the list of antioxidant compounds in the roots of D. hamiltonii.

Item Type: Article
Uncontrolled Keywords: EXTRACTS-; ORGANIC-ACIDS; OXIDATION-; PHENOLS-; PLANTS-; ANTIOXIDATIVE-ACTIVITY; DECALEPIS-HAMILTONII; ELLAGIC-ACID; RADICAL-SCAVENGING-ACTIVITY
Subjects: 500 Natural Sciences and Mathematics > 10 Plants > 06 Trees And Shrubs
600 Technology > 08 Food technology > 32 Antioxidants
Divisions: Food Protectants and Infestation Control
Plantation Products Spices and Flavour Technology
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 13 Aug 2008 10:04
Last Modified: 19 Jul 2012 04:10
URI: http://ir.cftri.com/id/eprint/8080

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