[feed] Atom [feed] RSS 1.0 [feed] RSS 2.0

Structural studies on the non-toxic lipid A from Rhodopseudomonas sphaeroides ATCC 17023

Salimath, P. V. and Jürgen, Weckesser and Wolfgang, Strittmatter (1983) Structural studies on the non-toxic lipid A from Rhodopseudomonas sphaeroides ATCC 17023. European Journal of Biochemistry, 136 (1). pp. 195-200.

[img] PDF
eur_j_biochem_1983_195.pdf
Restricted to Registered users only

Download (1MB)

Abstract

The lipid A isolated from Rhodopseudomonas sphaeroides ATCC 17023 has been investigated. A sequence of analyses indicated β-D-glucosaminyl-1,6-D-glucosamine as the sugar backbone carrying phosphate groups at C-1 of the reducing glucosamine and C-4 of the non-reducing glucosamine. Both 3-(7-tetradecenoyl)oxytetradecanoic and 3-oxotetradecanoic acid are linked to the NH2 groups. Two residues of 3-hydroxydecanoic acid are linked to hydroxy groups at C-3 of both reducing and non-reducing glucosamine, and the hydroxy group of 3-hydroxydecanoic acid is free. In free lipid A, the hydroxy group at C-4 of the reducing glucosamine and at C-6 of the non-reducing glucosamine are unsubstituted. The latter probably arises from a 3-deoxy-D-manno-octulosonate linkage. The structural similarities and dissimilarities existing between lipid A of R. sphaeroides, which is non-toxic, and lipid A types such as those from Salmonella, which are toxic, are discussed.

Item Type: Article
Uncontrolled Keywords: lipid A, Rhodopseudomonas sphaeroides
Subjects: 500 Natural Sciences and Mathematics > 07 Life Sciences > 04 Microbiology > 02 Bacteriology
500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 28 Polysaccharide Chemistry
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 26 Sep 2010 09:10
Last Modified: 28 Dec 2011 10:00
URI: http://ir.cftri.com/id/eprint/7789

Actions (login required)

View Item View Item