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Studies on urinary arylsulphatase activity in vitamin A deficient rats.

Srinivas, L. and Rao, P. B. R. (1976) Studies on urinary arylsulphatase activity in vitamin A deficient rats. International Journal of Vitamin and Nutrition Research, 46. pp. 3-10.

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Abstract

Weanling Wistar rats of both sexes had vitamin A-deficient diets until growth was retarded or they were acutely deficient, when they were transferred to metabolism cages and 24-h urine was collected; creatinine, nondialysable N and arylsulphatase (EC 3.1.61) activity were estimated and correlated with liver vitamin A in the vitamin A-deficient and a similar group of rats given supplementary vitamin. The effects of starvation, followed by refeeding or a single dose of vitamin A, were also examined in adult rats. There was a significant reduction in urinary sulphatase A and B activities in vitamin A-deficient male rats, whilst depression of arylsulphatase A activity only was observed in the females; these effects were evident at the 'weight plateau' stage, before reduction in food intake or bodyweight occurred. In male rats starved for 24 h, urinary sulphatase A and B activities increased; oral dosage of retinyl acetate caused a significant fall in activity of both enzymes; refeeding brought a return to normal only for arylsulphatase A.

Item Type: Article
Uncontrolled Keywords: vitamin-A-deficiency
Subjects: 600 Technology > 08 Food technology > 16 Nutritive value > 04 Vitamins
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 14 Jul 2016 07:59
Last Modified: 14 Jul 2016 07:59
URI: http://ir.cftri.com/id/eprint/6556

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