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Toxic and antigrowth effects of raw and processed field bean (Dolichos lablab) on albino rats.

Ramamani, S. and Subramanian, N. and Parpia, H. A. B. (1979) Toxic and antigrowth effects of raw and processed field bean (Dolichos lablab) on albino rats. Journal of Biosciences, 1. pp. 241-253.

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Samples of freeze dried green field bean (Dolichos lablab) and dry mature bean, were subjected to the following processing methods-heat processing, extraction with 80"10 ethanol, hexane or dilute acid, protein isolation; and these samples were evaluated for growth promoting value and toxicity. Extraction with 80% ethanol or with dilute acid increased survival period of the animals; but these did not promote growth. Heat processing was essential to destroy antinutritional factors and promote growth. Extraction of the beans with 80% ethanol did not however alter the trypsin inhibitor or haemagglutinin activities. The protein isolate and acid-extracted residue which had low trypsin inhibitor and haemagglutinin activities, did not also promote growth. Thus the trypsin inhibtor and baemagglutinin activities did not completely account for the toxicity to albino rat. How. ever, heat processing of ethanol extracted bean flour indicated that the beneficial effect of ethanol extraction was not apparent, once the samples were heat processed. Dry mature bean dhal was more toxic than the whole bean either dry or green. Supplementation of heat processed field bean with methionine and tryptophan promoted good growth of albino rats and significantly increased the protein efficiency ratio.

Item Type: Article
Uncontrolled Keywords: Trypsin inhibitor; haemagglutinin; processing; nutritive value; Dolichos lablab (field bean).
Subjects: 600 Technology > 01 Medical sciences > 17 Toxicology
600 Technology > 08 Food technology > 22 Legumes-Pulses
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 17 Nov 2014 07:15
Last Modified: 17 Nov 2014 07:15
URI: http://ir.cftri.com/id/eprint/6112

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