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The effect of maternal diet low in vitamin A on brain constituents of preweanling rats.

Bhat, P. V. and Rama Rao, P. B. (1976) The effect of maternal diet low in vitamin A on brain constituents of preweanling rats. Arogya, 2. pp. 96-102.

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Abstract

The effect of maternal diet 'low' in vitamin A during pregnancy and lactation on the brain lipid components of offspring during the preweaning period was studied. Brain lipid constituents, DNA and protein of ID-17 day old rats from mother rats given 100 I.V. or 10 lV. of vitamin A acetate per day were estimated. Comparative data on brain lipids of infants rats 'undernourished' from birth till day were also obtained. Body and brain weights of pups born to mother rats on 'low~ vitamin A diets were significantly reduced. Decreases in brain cholesterol and an altered pattern of accumulation of gangliosides were observed in preweaning rats. Significant reduction in brain gangliosides of 17 day old rats was observed in the 'low' vitamin A group but not in the 'undernourished' rats of the same age. The significance of these findings on the possible need for vitamin A for normal brain development in the rat during the suckling period is discussed.

Item Type: Article
Uncontrolled Keywords: preweaning, lipid components, brain, vitamin A
Subjects: 600 Technology > 01 Medical sciences > 11 Malnutrition
600 Technology > 08 Food technology > 16 Nutritive value > 04 Vitamins
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 05 Feb 2015 05:46
Last Modified: 05 Feb 2015 05:46
URI: http://ir.cftri.com/id/eprint/5991

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