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Studies on liver and plasma hexosamine: Effect of low protein diet with or without supplement of L-cystine or DL-ethionine.

Srinivas, H. and Rama Rao, P. B. (1970) Studies on liver and plasma hexosamine: Effect of low protein diet with or without supplement of L-cystine or DL-ethionine. Nutrition Reports International, 2 (6). pp. 319-330.

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Abstract

The incidence of fatty infiltration of liver in rats maintained on low protein diets (casein, ragi and maize) was studied in relation to levels of protein bound hexosamine in -liver and plasma. The effect of dietary supplement of DL-Ethionine or L-cystine to casein diets (5-9% protein) was also investigated. A decrease in plasma hexosamine and indication of increased accumulation of lipid in livers of rats maintained on ragi and maize diets was observed. Increase in liver bound hexosamine was also observed in the group fed the maize diet whereas a decrease was observed in the ragi fed group'. L-cystine supplement (at 0.5% level) to casein diet resulted in generalised fatty livers prevented by further supplement of methionine and choline. Plasma protein-bound hexosamine was unchanged when maintained for two weeks. However, a significant increase in liver-bound hexosamine coupled with a decrease in plasma-protein bound hexosamine was observed in rats when the duration of the study was three weeks'. DL-Ethionine supplement at 0.1% level to a casein diet (9%) resulted in increased accumulation of lipids and bound hexosamine in livers of female rats. The serum-bound hexosamine was not affected at this level, but at more toxic levels, a decrease was observed.

Item Type: Article
Uncontrolled Keywords: low protein diets, casein, ragi, maize, liver, plasma
Subjects: 600 Technology > 01 Medical sciences > 11 Malnutrition
600 Technology > 08 Food technology > 16 Nutritive value > 03 Proteins
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 22 May 2012 09:22
Last Modified: 22 May 2012 09:22
URI: http://ir.cftri.com/id/eprint/5637

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