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Effect of vitamin A deficiency on the acid mucopolysaccharides of rat skin.

Leela, R. and Rama Rao, P. B. (1970) Effect of vitamin A deficiency on the acid mucopolysaccharides of rat skin. Nutrition Reports International, 2. pp. 305-318.

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Abstract

The effect of vitamin A deficiency on the incorporation of radioactive sulfate (N 37S014,) into the acid mucopolysaccharides of rat skin has been studied. Weanling rats were maintained on a vitamin A deficient diet and Na,37S0,. injected, into groups of rats at various stages of dtficiWncy. The MPS from the skin were isolated and their constituents - uronic acid, Hexosamine and Sulfate, protein and the 535 activity associated with the MPS determined. Similar data was obtained for MPS isolated from skins of vitamin A supplemented controls'. Fractionation of the MPS on DEAE-Sephadex was also carried out The results of these-studies show that vitamin A deficiency resulted in increased incorporation of S35 into rat skin MPS. The proportion of sulfated and non-sulfated MPS was also affected suggesting that vitamin A deficiency affects the turnover rate of sulfated and non-sulfated MPS of rat skin'.

Item Type: Article
Uncontrolled Keywords: vitamin A deficiency, mucopolysaccharides
Subjects: 600 Technology > 01 Medical sciences > 11 Malnutrition
600 Technology > 08 Food technology > 16 Nutritive value > 04 Vitamins
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 22 May 2012 09:11
Last Modified: 22 May 2012 09:11
URI: http://ir.cftri.com/id/eprint/4061

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