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Effect of turmeric extract on cholesterol levels in rats.

Srinivasan, M. and Aiyar, A. S. and Kapur, O. P. and Kokatnur, M. G. and Subba Rao, D. and Sreenivasan, A. and Subrahmanyan, V. (1964) Effect of turmeric extract on cholesterol levels in rats. Indian Journal of Experimental Biology, 2. pp. 104-107.

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In general, the effect of turm.eric extract on endogenous levels of cholesterol in the liver and serum of the rat is not appreciable. However, this effect is pronounced in counteracting the increment in liver cholesterol induced by feeding cholesterol, provided the feed ratio of the tunneric derivative to cholesterol is 1: 10; this effect is not seen when the ratio is I: SO. The pattern of results is similar with the total alcoholic extract of turtneric or its lipid·free fraction (crude curcumin), with the growing rat or the adult rat, fed with groundnut oil or its hydrogenated product. Tbe cholesterol levels reached in the liver of rats fed cholesterol are, however, higher with the unsaturated oil in the diet than with the saturated fat, Contrary to previous reports, an inexplicable result repeatedly noted is that cholesterol feeding does not perceptibly enhance the serum levels or the faecal excretion of sterols. The implications of the results and their relevance to human physiology are briefly discussed.

Item Type: Article
Uncontrolled Keywords: turmeric extract, cholesterol
Subjects: 600 Technology > 01 Medical sciences > 12 Metabolism
600 Technology > 08 Food technology > 30 Spices/Condiments
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 12 Feb 2014 11:47
Last Modified: 12 Feb 2014 11:47
URI: http://ir.cftri.com/id/eprint/4050

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