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Synthesis, Dimroth rearrangement and blood platelet disaggregation property of pyrimido [4',5':4,5] selenolo [2,3-b] quinolines: A new class of condensed quinoline.

Nandeeshaiah, S. K. and Ambekar, S. Y. and Krishnakantha, T. P. (1998) Synthesis, Dimroth rearrangement and blood platelet disaggregation property of pyrimido [4',5':4,5] selenolo [2,3-b] quinolines: A new class of condensed quinoline. Indian Journal of Chemistry, 37B (10). pp. 995-1000.

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Abstract

Compounds containing 4-aminoselenolo[3,2-d] pyrimidine in a novel tetracyclic condensed quinoline system viz. pyrimido[4',5':4,5]selenolo [2,3-b]quinoline have been synthesized. Dimroth rearrangement of this new condensed diazine system is studied. Biological study shows that while all compounds are active against collagen induced blood platelet aggregation, they are found to be inactive against ADP induced blood platelet aggregation.

Item Type: Article
Uncontrolled Keywords: Dimroth rearrangement, blood platelet aggregation, 4-aminoselenolo[3,2-d] pyrimidine
Subjects: 500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 24 Organic Chemistry
Divisions: Plantation Products Spices and Flavour Technology
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 12 Mar 2012 05:02
Last Modified: 12 Mar 2012 05:02
URI: http://ir.cftri.com/id/eprint/2941

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