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Effect of oryzanol on cholesterol absorption & biliary & fecal bile acids in rats.

Seetharamaiah, G. S. and Chandrasekhara, N. (1990) Effect of oryzanol on cholesterol absorption & biliary & fecal bile acids in rats. The Indian Journal of Medical Research, 92. pp. 471-5. ISSN 0971-5916

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Abstract

Effect of oryzanol on biliary secretion of cholesterol, phospholipid and bile acids and fecal excretion of cholesterol and bile acids was examined in male albino rats. Feeding oryzanol at 0.5 per cent level with the control diet did not cause any change in bile flow and composition. On feeding oryzanol with high cholesterol diet, the bile flow and total bile acid output were increased by 12 and 18 per cent respectively, while biliary cholesterol and phospholipids remained unchanged. The increased bile acid secretion was mainly due to taurocholic acid. In rats fed oryzanol along with high cholesterol diet, there was a significant increase in the fecal excretion of cholesterol (28%) and of bile acids (29%), whereas cholesterol absorption was lowered by 20 per cent.

Item Type: Article
Uncontrolled Keywords: oryzanol, biliary secretion, fecal excretion
Subjects: 600 Technology > 01 Medical sciences > 12 Metabolism
600 Technology > 08 Food technology > 19 Lipids-oils/fats
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 06 Apr 2018 04:52
Last Modified: 06 Apr 2018 04:52
URI: http://ir.cftri.com/id/eprint/2340

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