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Prenatal toxicity of heptachlor in albino rats.

Rani, B. E. A. and Krishnakumari, M. K. (1995) Prenatal toxicity of heptachlor in albino rats. Pharmacology and Toxicology, 76 (2). pp. 112-4. ISSN 0901-9928

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Abstract

Exposure of the cyclodiene insecticide heptachlor at 1/8 and 1/4 LD50 to male and female albino rats before mating affected fertility in both sexes. A decrease in implantations, serum oestrogen and progesterone levels and increase in resorptions in the females was observed. However, no histological changes were observed except for few atretic follicles in the treated females. In males, a dose-dependent significant decrease in the sperm count and coagulating gland fructose levels was observed, with marginal degeneration of seminiferous tubules. These results are indicative of the prenatal toxicity of heptachlor in male and female rats.

Item Type: Article
Uncontrolled Keywords: heptachlor insecticide toxicity
Subjects: 500 Natural Sciences and Mathematics > 04 Chemistry and Allied Sciences > 26 Pesticide Chemistry
600 Technology > 01 Medical sciences > 17 Toxicology
Divisions: Food Protectants and Infestation Control
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 05 Jan 2017 10:56
Last Modified: 05 Jan 2017 10:56
URI: http://ir.cftri.com/id/eprint/2258

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