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Isolation and characterization of antioxidant and antibacterial compound from mango ginger (Curcuma amada Roxb.) rhizome.

Policegoudra, R. S. and Abiraj, K. and Channe Gowda, D. and Aradhya, S. M. (2007) Isolation and characterization of antioxidant and antibacterial compound from mango ginger (Curcuma amada Roxb.) rhizome. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 852 (1-2). pp. 40-8. ISSN 1570-0232

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Abstract

The chloroform extract of mango ginger (Curcuma amada Roxb.) rhizome was subjected to antioxidant activity-guided purification by repeated silica gel column chromatography to obtain a pure antioxidant compound. The structure was deduced by analyzing UV, IR, liquid chromatography-mass spectrometry (LC-MS) and two-dimensional heteronuclear multiple quantum coherence transfer spectroscopy (2D-HMQCT) NMR spectral data, and named it as "Amadannulen", a novel compound. It exhibited DPPH radical scavenging activity, super oxide radical scavenging activity, lipid peroxidation inhibitory activity and metal chelating activity. Amadannulen also showed antibacterial activity against both Gram-positive and Gram-negative bacteria tested. It also exhibited bactericidal activity against M. luteus, B. cereus and B. subtilis.

Item Type: Article
Uncontrolled Keywords: Curcuma amada; Mango ginger; Rhizome; Antioxidant activity; Antibacterial activity; Amadannulen
Subjects: 600 Technology > 08 Food technology > 30 Spices/Condiments
600 Technology > 08 Food technology > 32 Antioxidants
Divisions: Fruit and Vegetable Technology
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 18 Aug 2008 10:08
Last Modified: 29 Dec 2016 11:20
URI: http://ir.cftri.com/id/eprint/1896

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