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Hypolipidemic Effect of Purslane (Portulaca oleracea L.) in Rats Fed on High Cholesterol Diet.

Niharika, Shanker and Sukumar, Debnath (2016) Hypolipidemic Effect of Purslane (Portulaca oleracea L.) in Rats Fed on High Cholesterol Diet. Journal of Nutrition and Food Sciences, 6 (6). pp. 1-8.

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Abstract

Purslane is a vegetarian source of n-3 PUFA (α-linolenic acid). The objective of the present work was to explore purslane as n-3 source to mitigate hyperlipidemia in rat model. Group of rats (n=48) were fed on high cholesterol diet to induce hyperlipidemia. Group 1,2,3,4 and 5 (n=6/group) were fed on aqueous extract of purslane (AEP) and lovastanin diet while group 6 and 7 were treated as hyperlipidemic and normal control. The results revealed a significant (p<0.05) reduction in serum TC, LDL-C, VLDL-C, TAG, increase in serum HDL-C level observed in AEP fed rats as compared to cholesterol induced hyperlipidemic control group. Groups treated with AEP and lovastatin also demonstrated considerable decrease in LDL-C: HDL-C ratios, levels of SGOT, SGPT, ALP activities and body weight in comparison to control group. Therefore, administration of AEP concluded that 150 mg/kg body weight AEP is a potent cardio-protective agent having preventive and curative effect against hyperlipidemia.

Item Type: Article
Uncontrolled Keywords: Purslane; Hypolipidemia; Drying; PUFA; Cardioprotective agent
Subjects: 500 Natural Sciences and Mathematics > 10 Plants
500 Natural Sciences and Mathematics > 07 Life Sciences > 03 Biochemistry & Molecular Biology > 11 Lipid Biochemistry
Divisions: Lipid Science and Traditional Foods
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 09 Jan 2018 08:10
Last Modified: 09 Jan 2018 08:10
URI: http://ir.cftri.com/id/eprint/13256

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