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Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Alliumsativum) alleviates oxidative stress in experimental myocardial infarction.

Mukthamba, P. and Srinivasan, K. (2017) Dietary fenugreek (Trigonella foenum-graecum) seeds and garlic (Alliumsativum) alleviates oxidative stress in experimental myocardial infarction. Food Science and Human Wellness, 6. pp. 77-87.

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Abstract

Soluble fiber-rich fenugreek seeds (Trigonella foenum-graecum) and garlic (Allium sativum) are understood to exert cholesterol-lowering andantioxidant effects. The cardioprotective influence of a combination of fenugreek seeds and garlic by their antioxidant influence was evaluatedin hypercholesterolemic rats administered isoproterenol. Wistar rats were maintained on high-cholesterol diet for 8 weeks along with dietaryinterventions of fenugreek (10%), garlic (2%) and their combination. Myocardial infarction was induced with isoproterenol injection. Increasedcirculatory troponin, disturbed activities of cardiac ATPases, increased serum iron and decreased ceruloplasmin confirmed myocardial infarction.Elevated lipid peroxides accompanied with reduced antioxidant molecules caused by isoproterenol and altered activities of antioxidant enzymes inserum and heart in induced myocardial necrosis were countered by dietary fenugreek, garlic, and fenugreek + garlic. Dietary fenugreek seeds andgarlic ameliorated

Item Type: Article
Uncontrolled Keywords: Fenugreek seeds; Garlic; High cholesterol diet; Isoproterenol; Myocardial infarction; Oxidative stress1
Subjects: 600 Technology > 08 Food technology > 18 Processed foods > 01 Dietary Fiber
600 Technology > 08 Food technology > 30 Spices/Condiments
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 22 Nov 2017 10:40
Last Modified: 22 Nov 2017 10:40
URI: http://ir.cftri.com/id/eprint/13163

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