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Effect of mango (Mangifera indica L.) peel on hyperglycemia and changes in crystallin during cataract formation in diabetic rats.

Mahendranath, Gondi (2016) Effect of mango (Mangifera indica L.) peel on hyperglycemia and changes in crystallin during cataract formation in diabetic rats. Doctoral thesis, Central Food Technological Research Institute.

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Abstract

Diabetes mellitus, commonly referred to as diabetes, is a metabolic disorder and it is characterized by hyperglycemia. Diabetes results from defects in insulin secretion, or insulin action or both. Several million people are affected with diabetes mellitus and the number of people with diabetes is projected to rise. Prolonged exposure to hyperglycemia is associated with long-term damage of dysfunction and failure of different organ, especially the eyes, kidneys, nerves, heart and blood vessels and leads to pathogenesis of diabetic complications. Hyperglycemia may increase oxidative stress via alterations of key metabolic pathways such as polyol pathway flux and increased AGEs formation. Patients suffering from diabetes are at an increased risk of developing cataract at an earlier age than people without diabetes.

Item Type: Thesis (Doctoral)
Uncontrolled Keywords: Diabetes mellitus dietary antioxidants nutraceuticals ripe mango peels
Subjects: 600 Technology > 01 Medical sciences > 04 Diabetes Mellitus
600 Technology > 08 Food technology > 18 Processed foods > 01 Dietary Fiber
600 Technology > 08 Food technology > 24 Fruits > 06 Mango
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 13 Jul 2017 09:33
Last Modified: 13 Jul 2017 09:33
URI: http://ir.cftri.com/id/eprint/12824

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