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Platelet aggregation inhibitory activity and radical scavenging activity of Spondias mangi/era Willd.

Sivaprasad, M. and Policegoudra, R. S. and Swaroop Kumar, H. M. and Aradhya, S. M. (2011) Platelet aggregation inhibitory activity and radical scavenging activity of Spondias mangi/era Willd. South Asian Journal of Experimental BioIogy, 1 (1). pp. 25-30.

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Abstract

The dry powder of Spondios mangifera Willd. fruits was sequentially extracted with hexane, chloroform, ethyl acetate, acetone and methanol. The extract yield increased with increase in the polarity of the solvent. The ethyl acetate extract showed potential platelet aggregation inhibitory activity with 1C50 value of 0.33 mg and 0.43 mg for antagonists like collagen and ADP respectively. The methanol extract also revealed high platelet aggregation inhibition with very low 1(50 value of 0.26 mg and 0.35 mg for antagonists like collagen and ADP respectively, Methanol extract showed high DPPH radical scavenging activity compared to other extracts,

Item Type: Article
Uncontrolled Keywords: Spondias mangifera, platelet aggregation, inhibitory activity, antioxidant activity, free radicals.
Subjects: 600 Technology > 08 Food technology > 24 Fruits
600 Technology > 08 Food technology > 32 Antioxidants
Divisions: Fruit and Vegetable Technology
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 23 Jun 2017 09:10
Last Modified: 23 Jun 2017 09:10
URI: http://ir.cftri.com/id/eprint/12654

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