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Aqueous extract of tomato seeds attenuates rotenone-induced oxidative stress and neurotoxicity in Drosophila melanogaster

Gokul, Krishna and Dr., Muralidhara (2016) Aqueous extract of tomato seeds attenuates rotenone-induced oxidative stress and neurotoxicity in Drosophila melanogaster. Journal of the Science of Food and Agriculture, 96. pp. 1745-1755.

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Abstract

BACKGROUND: Tomato seeds, amajor by-product fromthe food processing industry, constitute a rich source of bioactives and a large population consumes tomato (either in raw or cooked form). In the present study, initially we assessed the antioxidant activity of aqueous extract of tomato seeds (TSE) in selected chemical systems and further explored the neuroprotective effects of TSE utilising the rotenone (ROT)model of neurotoxicity in Drosophila. RESULTS: Adultmale flies (Oregon K) were fed TSE-enriched medium (0.1–0.2%) with or without ROT (500

Item Type: Article
Uncontrolled Keywords: tomato; seeds; Drosophila; rotenone; oxidative stress; neurotoxicity; protection
Subjects: 600 Technology > 01 Medical sciences > 17 Toxicology
600 Technology > 08 Food technology > 23 Vegetables > 03 Tomato
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 08 Nov 2016 10:46
Last Modified: 08 Nov 2016 10:46
URI: http://ir.cftri.com/id/eprint/12422

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