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Studies on catabolite repression in solid state fermentation for biosynthesis of fungal amylases

Nandakumar, M. P. and Thakur, M. S. and Raghavarao, K. S. M. S. and Ghildyal, N. P. (1999) Studies on catabolite repression in solid state fermentation for biosynthesis of fungal amylases. Letters in Applied Microbiology, 29. pp. 380-384.

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Catabolite repression by glucose of the biosynthesis of alpha amylase and amyloglucosidase by Aspergillus niger CFTRI 1105 was studied in a solid state fermentation (SSF) and in submerged fermentation (SMF) systems and the results were compared. The addition of glucose did not enhance the production of alpha-amylase and amyloglucosidase in an earlier fermentation system. However, a drastic reduction in alphaamylase production was observed in submerged fermentation by the addition of 5·0 mg ml-1 glucose and of amyloglucosidase production by 10 mg ml-1 glucose. Glucose concentrations above 50 mg ml-1 completely suppressed the production of both enzymes in the initial hours. In contrast, in the SSF system the repression was negligible, even when the glucose level was raised to 150 mg g�1 wheat bran for both alpha and amyloglucosidase synthesis.

Item Type: Article
Uncontrolled Keywords: biosynthesis alpha amylase amyloglucosidase Aspergillus niger solid state fermentation submerged fermentation catabolite enzymes
Subjects: 600 Technology > 05 Chemical engineering > 04 Fermentation Technology
500 Natural Sciences and Mathematics > 07 Life Sciences > 04 Microbiology > 04 Fungi
Divisions: Fermentation Technology and Bioengineering
Food Engineering
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 22 Jun 2007 08:53
Last Modified: 28 Dec 2016 11:18
URI: http://ir.cftri.com/id/eprint/1241

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