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Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation

Chidananda, C. and Vasantha, K. Y. and Sattur, A. P. (2015) Sclerotiorin is non-mutagenic and inhibits human PMNL 5-lipoxygenase and platelet aggregation. Indian Journal of Experimental Biology, 53 (4). pp. 228-231.

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Abstract

Sclerotiorin, isolated from the fermented broth of Penicillium frequentans, exhibited potent inhibition against human polymorphonuclear leukocytes 5-lipoxygenase and human platelet aggregation with a half maximal value 36 µM and 250 µM, respectively. Further, the Ames test has demonstrated the sclerotiorin to be non-mutagenic.

Item Type: Article
Uncontrolled Keywords: Ames test Fungal azaphilone Penicillium frequentans
Subjects: 500 Natural Sciences and Mathematics > 07 Life Sciences > 04 Microbiology > 04 Fungi
Divisions: Fermentation Technology and Bioengineering
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 18 May 2016 06:11
Last Modified: 18 May 2016 06:11
URI: http://ir.cftri.com/id/eprint/12147

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