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Soy whey based medium for optimized phytase activity in Saccharomyces cerevisiae MTCC 5421 and α-D-galactosidase and antibacterial activities in Lactobacillus plantarum MTCC 5422 by response surface methodology

Mahendranath, Gondi and Shaik Akbar, Basha and Jamuna, J. Bhaskar and Salimath, P. V. and Prasada Rao, U. J. S. (2015) Soy whey based medium for optimized phytase activity in Saccharomyces cerevisiae MTCC 5421 and α-D-galactosidase and antibacterial activities in Lactobacillus plantarum MTCC 5422 by response surface methodology. Journal of the Science of Food and Agriculture, 95. pp. 991-999.

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Abstract

BACKGROUND: In the present study, the composition of mango peel powder (MPP) collected fromthe mango pulp industrywas determined and the effect ofMPP on ameliorating diabetes and its associated complications was studied. RESULTS: Mango peel was rich in polyphenols, carotenoids and dietary fibre. Peel extract contained various bioactive compounds and was found to be rich in soluble dietary fibre. Peel extract exhibited antioxidant properties and protected against DNA damage. Therefore, the effect of peel on ameliorating diabetes was investigated in a rat model of diabetes. A significant increase in urine sugar, urine volume, fasting blood glucose, total cholesterol, triglycerides and low density lipoprotein, and decrease in high density lipoprotein were observed in the rats; however, these parameters were ameliorated in diabetic rats fed with diet supplemented withmango peel at 5% and 10% levels in basal diet. Treatment of diabetic rats with MPP increased antioxidant enzyme activities and decreased lipid peroxidation in plasma, kidney and liver compared to untreated diabetic rats. Glomerular filtration rate and microalbuminuria levels were ameliorated inMPP treated diabetic group. CONCLUSIONS: Mango peel, a by-product, can be used as an ingredient in functional and therapeutic foods.

Item Type: Article
Uncontrolled Keywords: diabetes; mango peel; antioxidant enzymes; streptozotocin induced diabetes; oxidative stress
Subjects: 600 Technology > 01 Medical sciences > 04 Diabetes Mellitus
600 Technology > 08 Food technology > 24 Fruits > 06 Mango
600 Technology > 08 Food technology > 32 Antioxidants
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 16 Jun 2015 07:32
Last Modified: 16 Jun 2015 07:32
URI: http://ir.cftri.com/id/eprint/11802

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