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Bioefficacy of EPA–DHA from lipids recovered from fish processing wastes through biotechnological approaches.

Amit Kumar, Rai and Bhaskar, N. and Baskaran, V. (2013) Bioefficacy of EPA–DHA from lipids recovered from fish processing wastes through biotechnological approaches. Food Chemistry, 136 . pp. 80-86. ISSN 0308-8146

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Abstract

The effect of fish oil recovered from fish visceral waste (FVW-FO) on serum and liver lipids, activity of HMG-CoA reductase in liver microsomes and EPA + DHA incorporation in liver, heart and brain were evaluated. Rats were fed different concentrations of FVW-FO providing 1.25%, 2.50%, 5.0% EPA + DHA recovered by either fermentation or enzymatic hydrolysis for 8 weeks. Feeding FVW-FO reduce triacylglycerols (5.96–20.3%), total cholesterol (7.9–21.5%) and LDL (7.39–21.7%) cholesterol levels in serum compared to group fed on a control diet (groundnut oil). The activity of HMG-CoA reductase was reduced (p < 0.05) in the FVW-FO fed groups compared to the control. EPA + DHA level in serum, liver, brain and heart increased with increments in dietary EPA + DHA. Results show the hypolipidemic property of FVW-FO and reduced HMG-CoA reductase activity which is proportional to the incorporation of EPA + DHA. Recovery of FVW-FO will address the increasing demand for fish oil and reduce pollution problems.

Item Type: Article
Uncontrolled Keywords: Fish visceral waste, Fermentation Enzymatic hydrolysis, EPA, DHA HMG-CoA reductase
Subjects: 500 Natural Sciences and Mathematics > 07 Life Sciences > 03 Biochemistry & Molecular Biology > 11 Lipid Biochemistry
600 Technology > 08 Food technology > 16 Nutritive value > 05 Enzymes
600 Technology > 08 Food technology > 28 Meat, Fish & Poultry > Fish
Divisions: Dept. of Biochemistry
Meat Fish and Poultry Technology
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 27 Aug 2012 09:19
Last Modified: 10 Nov 2016 12:40
URI: http://ir.cftri.com/id/eprint/10965

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