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Effect of feeding blended and interesterified vegetable oils on antioxidant enzymes in rats

Reena, Malongil. B. and Lokesh, B. R. (2011) Effect of feeding blended and interesterified vegetable oils on antioxidant enzymes in rats. Food and Chemical Toxicology , 49. pp. 136-143.

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Abstract

The present study was undertaken to evaluate the effect of feeding blended and interesterified oils prepared using coconut oil (CNO) with rice bran oil (RBO) or sesame oil (SESO), with a polyunsaturated/saturated (P/S) ratio of 0.8–1.0, on oxidative stress and endogenous antioxidant system. Feeding blended oils resulted in significantly increased hepatic lipid peroxide levels in rats given blended oil CNO + RBO or CNO + SESO by 1.3 and 1.6-fold, respectively compared to rats fed diet containing CNO. The lipid peroxide level in erythrocyte membrane also increased in rats fed blended oil compared to rats fed with CNO. Rats fed interesterified oils prepared from these blended oils also showed increased lipid peroxide level compared to rats given CNO diet, however it was not significantly different from rats fed with their respective blends. There was a significant increase in the activity of endogenous antioxidant enzymes super oxide dismutase, catalase, glutathione peroxidase and glutathione-s-transferase after feeding blended and interesterified oils. The activities of Na+/K+-ATPase and Ca2+/Mg2+-ATPase were increased in rats fed blended and interesterified oils. These results indicated that the P/S ratio of dietary fat is an important factor in determining the oxidative stress, activity of endogenous antioxidant enzymes and activity of membrane bound enzymes.

Item Type: Article
Uncontrolled Keywords: Coconut oil, Rice bran oil, Sesame oil, Blended oil Interesterified oils, Lipid peroxidation
Subjects: 600 Technology > 08 Food technology > 19 Lipids-oils/fats
600 Technology > 08 Food technology > 32 Antioxidants
Divisions: Lipid Science and Traditional Foods
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 08 Jun 2011 11:23
Last Modified: 30 Dec 2016 13:07
URI: http://ir.cftri.com/id/eprint/10092

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