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Effects of Rice Bran Oil Enriched with n-3 PUFA on Liver and Serum Lipids in Rats

Rajni, Chopra and Sambaiah, Kari (2009) Effects of Rice Bran Oil Enriched with n-3 PUFA on Liver and Serum Lipids in Rats. Lipids, 44:. pp. 37-46.

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Lipase-catalyzed interesterification was used to prepare different structured lipids (SL) from rice bran oil (RBO) by replacing some of the fatty acids with a-linolenic acid (ALA) from linseed oil (LSO) and n-3 long chain polyunsaturated fatty acids (PUFA) from cod liver oil (CLO). In one SL, the ALA content was 20% whereas in another the long chain n-3 PUFA content was 10%. Most of the n-3 PUFA were incorporated into the sn-1 and sn-3 positions of triacylglycerol. The influence of SL with RBO rich in ALA and EPA ? DHA was studied on various lipid parameters in experimental animals. Rats fed RBO showed a decrease in total serum cholesterol by 10% when compared to groundnut oil (GNO). Similarly structured lipids with CLO and LSO significantly decreased total serum cholesterol by 19 and 22% respectively compared to rice bran oil. The serum TAGs level of rats fed SLs and blended oils were also significantly decreased by 14 and 17% respectively compared to RBO. Feeding of an n-3 PUFA rich diet resulted in the accumulation of long chain n-3 PUFA in various tissues and a reduction in the long chain n-6 PUFA. These studies indicate that the incorporation of ALA and EPA ? DHA into RBO can offer health benefits.

Item Type: Article
Uncontrolled Keywords: Rice bran oil � n-3 PUFA � Linseed oil � Cod liver oil � Enzymatic acidolysis � Serum lipids � Liver lipids
Subjects: 600 Technology > 08 Food technology > 19 Lipids-oils/fats
Divisions: Dept. of Biochemistry
Depositing User: Food Sci. & Technol. Information Services
Date Deposited: 07 Jun 2011 07:06
Last Modified: 28 Dec 2011 10:23
URI: http://ir.cftri.com/id/eprint/10082

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